Created in 1970, the ARC Foundation Léopold Griffuel Awards are one of the most prestigious international prizes dedicated exclusively to cancer research. These prizes reward a scientist or a research team, in France or abroad, whose work has led to a major breakthrough in cancer research. For an amount of €150,000 per laureate, these awards seek to promote and encourage further scientific projects.
Research can deal with all areas of cancer, from basic to translational and clinical research through 2 prize categories:
- Basic Research Award;
- Translational & Clinical Research Award
The application file must be submitted before June 30th, 2017.
The call for two Post-Doctoral positions in human science is available on this link
The Institute of Pharmacology and Structural Biology (IPBS, Toulouse-France) launches its International recruitment Program for New Group Leaders
Application deadline: July 15, 2017
Call Group leaders IPBS 2017
Founded in 1996, the Institute of Pharmacology and Structural Biology (IPBS) is a leading research institute of the French National Centre for Scientific Research (CNRS) and the University of Toulouse. Located on the main Campus of the Université Toulouse III-Paul Sabatier in Toulouse, southwest France, the IPBS offers multidisciplinary education in the fields of Science, Health, Engineering and Technology, developing one of the most important scientific research clusters in France.
The IPBS is a world leader in the discovery, characterization and validation of novel important pathways and pharmacological targets in the fields of cancer and infectious diseases, through the use of molecular and cellular biology approaches, together with in vivo experiments. It conducts state-of-the-art research in structural biology, proteomics, biophysics, cancerology, immunology and microbiology.
The IPBS brings together more than 250 scientists and supporting staffs, including more than 60 national and international postdoctoral fellows and PhD students. The IPBS offers outstanding scientific and stimulating research environment and several cutting-edge core facilities with highly qualified staff. These include mass spectrometry and proteomics, macromolecular crystallography, liquid- and solid-state NMR, biophysical characterization of proteins and complexes, virtual screening, whole body, tissue and cellular imaging, flow cytometry and cell sorting in standard or BSL3 environments, single particle tracking and tethered particle motion analysis, and animal facilities.
In order to reinforce its research endeavors in an inspiring, collaborative and cutting-edge environment, the IPBS is seeking new talented junior group leaders addressing fundamental questions within the spectrum of its research fields. Young scientists of any nationality, at junior or midcareer level, and with an excellent track record of publications in internationally recognized journals, are encouraged to apply. International experience as well as capacity to interact with other research groups within the institute are highly recommended.
Successful candidate(s) will be provided laboratory and office space for 5-8 people, a technical personnel and free access to the institute’s core facilities for a period of 2 years, together with a starting package for basic equipment and consumables. In addition, strong support will be provided from the IPBS to obtain tenured positions at CNRS, INSERM or the University of Toulouse. Outstanding candidates are expected to establish independent and vigorous national and international extramurally-funded research programs (ANR, ERC, etc.) that fit at least with one of the priority topics listed below. Researchers already holding a permanent position are also welcome to apply.
IPBS priority topics
See below full details for each topic
• Tumor microenvironment – Cancer immunology – Interactions of immune cells with stromal cells, the extracellular matrix and/or other immune cells; immune response to cancer.
• DNA repair/chromatin remodeling in cancer – DNA damage response (DDR) in connection with cancer through epigenetics, transcriptional regulation, DNA repair pathologies, chromosomal translocations, DDR-based drug discovery, or tumor resistance to clastogenic agents.
• Pulmonary infections – Biology of bacterial respiratory pathogens, with a strong focus on mechanisms underlying pathogen’s persistence, drug resistance or tolerance within the host.
• Drug discovery & structural biology – Development of biological and chemical drugs of the future, with the aim of strengthening the pharmacological aspects of the IPBS research framework; characterization of drug-target interactions and mechanism of action; “hit to lead” strategies and new approaches for drug target deconvolution or vectorization will be favored. A particular attention will be given to candidates willing to create a group in biological NMR.
Procedure & calendar
Application (about 5 pages in English) should include a cover letter describing previous research experience, an outline of the future research project, motivation for joining the institute and names and e-mail address of 3 referees, together with an updated CV (including a complete list of publications). Application should be sent to email@example.com in a single PDF file named LASTNAME_FIRSTNAME_IPBS2017.pdf. Other formats will not be considered.
Pre-selection: September 2017
Interviews: Mid-October 2017
Result: Early November 2017
New groups are expected to open in fall 2018 (National selection process for tenured positions will take place between January and April 2018)
Deadline for application: July 15, 2017
Bulletin de veille science et technologie – Ambassade de France en Australie – Science and Technology Newsletter – Embassy of France in Australia
The Embassy of France is delighted to send you the Science and Technology Newsletter for May 2017.
L’Ambassade de France en Australie a le plaisir de vous adresser l’édition de mai 2017 du bulletin de veille Science et Technologie édité par le poste.
Starch is a versatile product. In addition to being a major source of carbohydrates in people’s diets it has well over 700 non-food derived applications, such as in bulking agents, paper and adhesive.
Many biological and industrial processes, such as mammal digestion, plant metabolism and biofuel production, rely on the hydrolysis of native starch by amylolytic enzymes. These enzymes, represented mostly by α-amylases, break down the starch macromolecules to small carbohydrates and finally simple glucose molecules.
The Cereal Quality Group of CSIRO Agriculture and Food, based in Canberra, together with INRA Unité de Recherches Biopolymères, Interactions et Assemblages in Nantes, have developed a strong common interest in studying the impact of α-amylase in cereal quality and food production.
One such research interest is the beneficial effects α-amylase on bread quality and malting. It is thought that the addition of α-amylase results in the production of fermentable sugar, via starch hydrolysis, thereby fuelling fermentation. In baking, it contributes to shorter fermentation and increases loaf volume.
At the laboratory scale, it has been shown that starch digestion is governed by (1) the type of enzyme digesting the starch. (Each enzyme has a proper mode of action depending on the specific substrate) and (2) the structure and morphology of the starch granule. However, the influence of starch structure on amylolysis in industrial processes remains unclear.
In collaboration with Synchrotron SOLEIL (Paris), researchers have used the unique high-resolution UV imaging setup of the DISCO beamline to localize at high resolution, α-amylase action on starch without staining or use of a fluorescent probe. Like a precise amylase GPS, this has enabled researchers to follow, live and in 3D, the mode of action of a-amylase and the associated morphological changes of starch granules at different stages of their hydrolysis.
As part of the CSIRO/INRA linkage, researchers are now developing a model using a large wheat populations that will predict the degradability of wheat starches by industry grade baking improver α-amylases. This model would make possible to predict starch degradability by commercial α-amylases based on genetic information or structural analysis. It would also provide valuable information on new ways to tailor starch for industrial purposes, for both baking and malting as well as green chemistry and biofuel production.
Kamal KANSOU, Materials Processing and Behavior team, Bioplymeres Interactions Assemblages
Dr Jean-Philippe Ral, Cereal Quality, Crop improvement for novel products
IMPACT7 is a new event to be held on 1 August at Melbourne’s Meat Market.
The organisers, SlatteryIT, are looking for research innovators to present their projects to industry and public. Their focus is on projects that are solving wicked problems and producing research with impact in one of IMPACT7’s 7 Challenges.
Each successful applicant will receive important feedback and guidance, the chance to win a host of valuable prizes, and opportunities to network with leaders across Australian industry, research, and government.
Please encourage your most innovative researchers to take a look at www.impact7.com.au/apply
Thirty #womeninscience are being offered support and training to become superstars of STEM and role models for the next generation.
Superstars of STEM will smash society’s gender assumptions about scientists and increase the public visibility of women in STEM.
Science and Technology Australia (STA) are looking for 30 of the nation’s most dynamic scientists and technologists to create role models for young women and girls.
They’ll receive training in advanced communication skills and have opportunities to use them – in the media, on the stage, and in speaking with decision-makers.
Applications close on 23 May and full information is available on the STA website.